Engineering the mechanics of blood clotting
We study how physical forces regulate blood cells, vessels, and clot formation. By combining microfluidics, biomechanics, and artificial intelligence, we translate fundamental mechanobiology into diagnostic technologies and clinical solutions for thrombosis and cardiovascular disease.
Focus Areas
i. Shear-driven platelet biology
ii. Cellular mechanosensing (PIEZO1, cytoskeleton mechanics)
iii. Thrombosis-on-a-chip
iv. AI diagnostics (SmartClot)
v. Translational cardiovascular mechanobiology
Prof Arnold Ju’s research focuses on developing innovative microtechnologies for blood clot diagnosis and monitoring, benefiting disadvantaged populations. Through collaborative research and industry partnerships, the Ju-Snow Mechanobiology and Biomanufacturing Laboratory aims to translate discoveries into tangible healthcare solutions.
Our lab, led by Prof Arnold Ju and through collaborations with the Charles Perkins Centre, Sydney Nano, Heart Research Institute and RPA Hospital, is currently developing biomechanical nanotools, artificial intelligence imaging and mechanical medical screening platforms to predict, diagnose and treat disease as the point of care for the future.
Learn about our research
Our research aims to transform disease detection and treatment by uncovering the mechanobiology of thrombosis, discovering next-generation mechanomedicines, developing personalised mechanobiology-on-a-chip platforms, and translating these advances into point-of-care microdevices for faster, more accessible, and more precise diagnostics and therapies.
Meet our team
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